Inside Pediatrics Magazine Fall/Winter 2025

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HEMATOLOGY & ONCOLOGY

Aye appointed director of Developmental Therapeutics As the new director of Developmental Therapeutics,

Inside Pediatrics provides information, news and the latest updates from departments and divisions at Children’s of Alabama. Articles and features cover the current developments and discoveries related to pediatric medical research, clinical trials and treatments happening today. Inside Pediatrics helps keep you connected and up-to-date on the latest breakthroughs and medical advances at Children’s of Alabama.

Jamie Aye, M.D., aims to improve patient outcomes through the development of new clinical trials. Aye, an associate professor at UAB, was appointed director of the program in July after serving as associate director since 2023. In that role, she worked toward the mission of discovering, developing and delivering more effective and less toxic therapies for children

with cancer and blood disorders through translational research and early-phase clinical trials. In her new role, she will focus on research collaborations to advance clinical trials. “My vision is to improve the outcomes for patients with childhood cancer and blood disorders by strengthening collaborations between researchers locally at UAB and with researchers nationally,” Aye said. “Through these collaborations and in partnership with the Pediatric Clinical Trials Office, my goal is to develop cutting-edge, investigator-initiated trials here at Children’s of Alabama.” The Developmental Therapeutics Program is part of the Division of Hematology, Oncology, and Blood & Marrow Transplantation at UAB and Children’s. Its purpose is to improve the cure rate of pediatric cancers and blood disorders while also decreasing immediate and long-term side effects experienced by children undergoing treatment. Patients referred to the program typically have recurrent or refractory malignancies that have failed standard therapies. Other patients may be diagnosed with rare tumors for which no effective therapies have been established. DIVISION ROUNDS is a brief roundup of the innovative work Children’s of Alabama’s medical experts are doing in various divisions around the hospital. It showcases how we’re improving patient care and influencing the world of medicine. For more details and to find similar stories, please visit InsidePeds.org .