Inside Pediatrics Spring 2025

The Neurofibromatosis Clinical Trials Consortium Improving the quality of life of persons with neurofibromatosis

PARTICIPATING HOSPITALS 24

CLINICAL TRIALS 17

PEER-REVIEWED PAPERS 19+

INVESTIGATORS 72+

IN FUNDING $ 5M+

The Neurofibromatosis Clinical Trials Consortium brings together clinical centers with special expertise in the management of neurofibromatosis and links them together with a central operations center. The operations center, based at the University of Alabama at Birmingham, helps to organize the trials and ensure that all of the necessary regulations regarding clinical trials are followed. Having multiple centers participating around the country makes it easier to recruit a sufficient number of participants to obtain reliable conclusions. Since the discovery of the genes responsible for the different forms of neurofibromatosis, much has been learned about how the various problems associated with neurofibromatosis come about. This opens the door toward development and testing of medications that may be helpful in preventing or treating complications of the disorders. The consortium was formed in 2006 with funding from the U.S. Army Medical Research and Materiel Command to carry out clinical trials of such medications.

FOR MORE INFORMATION, VISIT UAB.EDU/NFCONSORTIUM/

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